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Evolutionary history and functional implications of protein domains and their combinations in eukaryotes

BACKGROUND: In higher multicellular eukaryotes, complex protein domain combinations contribute to various cellular functions such as regulation of intercellular or intracellular signaling and interactions. To elucidate the characteristics and evolutionary mechanisms that underlie such domain combina...

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Detalles Bibliográficos
Autores principales:	Itoh, Masumi, Nacher, Jose C, Kuma, Kei-ichi, Goto, Susumu, Kanehisa, Minoru
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394772/ https://www.ncbi.nlm.nih.gov/pubmed/17588271 http://dx.doi.org/10.1186/gb-2007-8-6-r121

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