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TP53 mutations in vulval lichen sclerosus adjacent to squamous cell carcinoma of the vulva

Non-neoplastic epithelial lesions of the vulva (NNEDV) lichen sclerosus (LS) and squamous hyperplasia (SH) have been implicated in the pathogenesis of squamous cell carcinoma of the vulva (SCC). To date, there have been no recognisable precursor lesions for SCC associated with NNEDV. TP53 is the mos...

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Detalles Bibliográficos
Autores principales:	Rolfe, K J, MacLean, A B, Crow, J C, Benjamin, E, Reid, W M N, Perrett, C W
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2003
Materias:	Molecular and Cellular Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395288/ https://www.ncbi.nlm.nih.gov/pubmed/14676802 http://dx.doi.org/10.1038/sj.bjc.6601444

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