Cargando…

Potential use of the alkaline comet assay as a predictor of bladder tumour response to radiation

Bladder tumours show a variable response to radiotherapy with only about 50% showing good local control; currently there is no test to predict outcome prior to treatment. We have used five bladder tumour cell lines (T24, UM-UC-3, TCC-SUP, RT112, HT1376) to investigate the potential of the alkaline c...

Descripción completa

Detalles Bibliográficos
Autores principales:	McKeown, S R, Robson, T, Price, M E, Ho, E T S, Hirst, D G, McKelvey-Martin, V J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2003
Materias:	Molecular and Cellular Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395295/ https://www.ncbi.nlm.nih.gov/pubmed/14676804 http://dx.doi.org/10.1038/sj.bjc.6601426

Ejemplares similares

Measurements using the alkaline comet assay predict bladder cancer cell radiosensitivity
por: Moneef, M A L, et al.
Publicado: (2003)

Detection of replicative integrity in small colonic biopsies using the BrdUrd comet assay
por: McGlynn, A P, et al.
Publicado: (2003)

Relationship between clonogenic radiosensitivity, radiation-induced apoptosis and DNA damage/repair in human colon cancer cells
por: Dunne, A L, et al.
Publicado: (2003)

Use of the Comet-FISH Assay to Compare DNA Damage and Repair in p53 and hTERT Genes following Ionizing Radiation
por: McKenna, Declan J., et al.
Publicado: (2012)

Tumour microvessel density as predictor of chemotherapy response in breast cancer patients
por: Tynninen, O, et al.
Publicado: (2002)

Lung resistance-related protein as a predictor of clinical outcome in advanced testicular germ-cell tumours
por: Zurita, A J, et al.
Publicado: (2003)

Retinoblastoma protein expression is an independent predictor of both radiation response and survival in muscle-invasive bladder cancer
por: Agerbaek, M, et al.
Publicado: (2003)

High level amplification of N-MYC is not associated with adverse histology or outcome in primary retinoblastoma tumours
por: Lillington, D M, et al.
Publicado: (2002)

GLUT1 and CAIX as intrinsic markers of hypoxia in bladder cancer: relationship with vascularity and proliferation as predictors of outcome of ARCON
por: Hoskin, P J, et al.
Publicado: (2003)

p53 and VEGF expression are independent predictors of tumour recurrence and survival following curative resection of gastric cancer
por: Fondevila, C, et al.
Publicado: (2004)

Tumour stage, node stage, p53 gene status, and bcl-2 protein expression as predictors of tumour response to platin-fluorouracil chemotherapy in patients with squamous-cell carcinoma of the head and neck
por: Fouret, P, et al.
Publicado: (2002)

Intra-tumoural microvessel density in human solid tumours
por: Hasan, J, et al.
Publicado: (2002)

Identifying pre-post chemotherapy differences in gene expression in breast tumours: a statistical method appropriate for this aim
por: Korn, E L, et al.
Publicado: (2002)

The embedded tumour: host physiology is important for the evaluation of tumour growth
por: van Leeuwen, I M M, et al.
Publicado: (2003)

Nuclear expression of Survivin in paediatric ependymomas and choroid plexus tumours correlates with morphologic tumour grade
por: Altura, R A, et al.
Publicado: (2003)

Galanin and galanin receptor expression in neuroblastic tumours: correlation with their differentiation status
por: Perel, Y, et al.
Publicado: (2002)

Differential expression of telomerase reverse transcriptase (hTERT) in lung tumours
por: Lantuejoul, S, et al.
Publicado: (2004)

The molecular pathology of p53 in primitive neuroectodermal tumours of the central nervous system
por: Burns, A S Y W, et al.
Publicado: (2002)

The coxsackievirus and adenovirus receptor acts as a tumour suppressor in malignant glioma cells
por: Kim, M, et al.
Publicado: (2003)

Prognostic impact of chromosomal aberrations in Ewing tumours
por: Hattinger, C M, et al.
Publicado: (2002)

Prediction of outcome in locally advanced breast cancer by post-chemotherapy nodal status and baseline serum tumour markers
por: Brenner, B, et al.
Publicado: (2002)

Quantitative analysis of human kallikrein gene 14 expression in breast tumours indicates association with poor prognosis
por: Yousef, G M, et al.
Publicado: (2002)

Expression of HER3, HER4 and their ligand heregulin-4 is associated with better survival in bladder cancer patients
por: Memon, A A, et al.
Publicado: (2004)

Faecal tumour M2 pyruvate kinase: a new, sensitive screening tool for colorectal cancer
por: Hardt, P D, et al.
Publicado: (2004)

Identification of heat shock protein 90 and other proteins as tumour antigens by serological screening of an ovarian carcinoma expression library
por: Luo, L-Y, et al.
Publicado: (2002)

Localisation of somatostatin and somatostatin receptors in benign and malignant ovarian tumours
por: Hall, G H, et al.
Publicado: (2002)

DNA replication licensing and cell cycle kinetics of oligodendroglial tumours
por: Wharton, S B, et al.
Publicado: (2004)

Thymidine phosphorylase expression in normal, hyperplastic and neoplastic prostates: correlation with tumour associated macrophages, infiltrating lymphocytes, and angiogenesis
por: Sivridis, E, et al.
Publicado: (2002)

FGFR3IIIS: a novel soluble FGFR3 spliced variant that modulates growth is frequently expressed in tumour cells
por: Sturla, L-M, et al.
Publicado: (2003)

Disturbed balance of expression between XIAP and Smac/DIABLO during tumour progression in renal cell carcinomas
por: Yan, Y, et al.
Publicado: (2004)

Discrimination between uterine serous papillary carcinomas and ovarian serous papillary tumours by gene expression profiling
por: Santin, A D, et al.
Publicado: (2004)

HPV infection and number of lifetime sexual partners are strong predictors for ‘natural’ regression of CIN 2 and 3
por: Chan, J K, et al.
Publicado: (2003)

Intense inflammation in bladder carcinoma is associated with angiogenesis and indicates good prognosis
por: Offersen, B V, et al.
Publicado: (2002)

The tumour–stromal interaction between intratumoral c-Met and stromal hepatocyte growth factor associated with tumour growth and prognosis in non-small-cell lung cancer patients
por: Masuya, D, et al.
Publicado: (2004)

Serum markers of matrix turnover as predictors for the evolution of colorectal cancer metastasis under chemotherapy
por: Hanke, B, et al.
Publicado: (2003)

Increased aquaporin 1 water channel expression inhuman brain tumours
por: Saadoun, S, et al.
Publicado: (2002)

DNA topoisomerase I and II expression in drug resistantgerm cell tumours
por: Berney, D M, et al.
Publicado: (2002)

Photodynamic therapy of DNA mismatch repair-deficient and -proficient tumour cells
por: Schwarz, V A, et al.
Publicado: (2002)

Cytotoxic T-cell precursor frequencies to HER-2 (369 – 377) in patients with HER-2/neu-positive epithelial tumours
por: Sotiropoulou, P A, et al.
Publicado: (2003)

Expression of different survivin variants in gastric carcinomas: first clues to a role of survivin-2B in tumour progression
por: Krieg, A, et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_6ov4qq0129gu2qekojrqjkl9al