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Encapsulation into sterically stabilised liposomes enhances the immunogenicity of melanoma-associated Melan-A/MART-1 epitopes
Tumour-associated antigens (TAA)-specific vaccination requires highly immunogenic reagents capable of inducing cytotoxic T cells (CTL). Soluble peptides are currently used in clinical applications despite an acknowledged poor immunogenicity. Encapsulation into liposomes has been suggested to improve...
Autores principales: | Adamina, M, Bolli, M, Albo, F, Cavazza, A, Zajac, P, Padovan, E, Schumacher, R, Reschner, A, Feder, C, Marti, W R, Oertli, D, Heberer, M, Spagnoli, G C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395333/ https://www.ncbi.nlm.nih.gov/pubmed/14710238 http://dx.doi.org/10.1038/sj.bjc.6601473 |
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