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Disruption of the MyoD/p21 Pathway in Rhabdomyosarcoma

Purpose. Rhabdomyosarcoma (RMS) is an embryonal tumor thought to arise from skeletal muscle cells that fail to differentiate terminally. The majority of RMSs express MyoD, a protein essential to the differentiation of skeletal muscle. It was recently shown that during myogenesis, MyoD activates the...

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Detalles Bibliográficos
Autores principales: Weintraub, Michael, Kalebic, Thea, Helman, Lee J., Bhatia, Kishor G.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395370/
https://www.ncbi.nlm.nih.gov/pubmed/18521215
http://dx.doi.org/10.1080/13577149778218