A Guideline for the Management of Gastrointestinal Stromal Tumour (GIST)

Gastrointestinal stromal tumour (GIST) is the commonest mesenchymal tumour to affect the gastrointestinal tract. Appropriate management requires accurate diagnosis and the skills of a multidisciplinary team. Surgery is the only curative treatment option and should be performed whenever feasible, by...

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Detalles Bibliográficos
Autores principales: Judson, Ian, Leahy, Michael, Whelan, Jeremy, Lorigan, Paul, Verrill, Mark, Grimer, Robert, Robinson, Martin
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2002
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395485/
https://www.ncbi.nlm.nih.gov/pubmed/18521337
http://dx.doi.org/10.1080/1357714021000045217
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author Judson, Ian
Leahy, Michael
Whelan, Jeremy
Lorigan, Paul
Verrill, Mark
Grimer, Robert
Robinson, Martin
author_facet Judson, Ian
Leahy, Michael
Whelan, Jeremy
Lorigan, Paul
Verrill, Mark
Grimer, Robert
Robinson, Martin
author_sort Judson, Ian
collection PubMed
description Gastrointestinal stromal tumour (GIST) is the commonest mesenchymal tumour to affect the gastrointestinal tract. Appropriate management requires accurate diagnosis and the skills of a multidisciplinary team. Surgery is the only curative treatment option and should be performed whenever feasible, by experienced personnel. For patients with advanced unresectable or metastatic disease, the receptor tyrosine kinase inhibitor imatinib offers effective therapy and can provide effective palliation for the majority of patients with this disease. The background to this recent development and a guideline for the management of GIST is proposed.
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spelling pubmed-23954852008-06-02 A Guideline for the Management of Gastrointestinal Stromal Tumour (GIST) Judson, Ian Leahy, Michael Whelan, Jeremy Lorigan, Paul Verrill, Mark Grimer, Robert Robinson, Martin Sarcoma Research Article Gastrointestinal stromal tumour (GIST) is the commonest mesenchymal tumour to affect the gastrointestinal tract. Appropriate management requires accurate diagnosis and the skills of a multidisciplinary team. Surgery is the only curative treatment option and should be performed whenever feasible, by experienced personnel. For patients with advanced unresectable or metastatic disease, the receptor tyrosine kinase inhibitor imatinib offers effective therapy and can provide effective palliation for the majority of patients with this disease. The background to this recent development and a guideline for the management of GIST is proposed. Hindawi Publishing Corporation 2002-09 /pmc/articles/PMC2395485/ /pubmed/18521337 http://dx.doi.org/10.1080/1357714021000045217 Text en Copyright © 2002 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Judson, Ian
Leahy, Michael
Whelan, Jeremy
Lorigan, Paul
Verrill, Mark
Grimer, Robert
Robinson, Martin
A Guideline for the Management of Gastrointestinal Stromal Tumour (GIST)
title A Guideline for the Management of Gastrointestinal Stromal Tumour (GIST)
title_full A Guideline for the Management of Gastrointestinal Stromal Tumour (GIST)
title_fullStr A Guideline for the Management of Gastrointestinal Stromal Tumour (GIST)
title_full_unstemmed A Guideline for the Management of Gastrointestinal Stromal Tumour (GIST)
title_short A Guideline for the Management of Gastrointestinal Stromal Tumour (GIST)
title_sort guideline for the management of gastrointestinal stromal tumour (gist)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395485/
https://www.ncbi.nlm.nih.gov/pubmed/18521337
http://dx.doi.org/10.1080/1357714021000045217
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