Differential Expression of IRS-1 and IRS-2 in Uterine Leiomyosarcomas with Distinct Oncogenic Phenotypes: Lack of Correlation with Downstream Signaling Events

Purpose: Insulin receptor substrates (IRSs) are essential for insulin-induced mitogenic effects on several cell types but they also are involved in cell transformation.We investigated whether the differential constitutive expression and potential distinct downstream signaling events of IRS-1 and IRS...

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Detalles Bibliográficos
Autores principales: Colombatti, Alfonso, Russo, Pietro, Cervi, Marta, Bogetto, Laura, Wassermann, Bruna, Mainiero, Fabrizio, Spessotto, Paola
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2002
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395487/
https://www.ncbi.nlm.nih.gov/pubmed/18521338
http://dx.doi.org/10.1080/1357714021000065387

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