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Periosteal Osteosarcoma: A Review of 17 Cases with Mean Follow-up of 52 Months

Purpose: Periosteal osteosarcomas are rare cartilage-rich bone tumours characterized by a juxtacortical eccentric position and are normally regarded oncologically as of intermediate to high grade.Their low incidence is mirrored by a small number of reported cases in the world literature. While there...

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Detalles Bibliográficos
Autores principales: Revell, Matthew P., Deshmukh, Neeta, Grimer, Robert J., Carter, Simon R., Tillman, Roger M.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395495/
https://www.ncbi.nlm.nih.gov/pubmed/18521348
http://dx.doi.org/10.1080/1357714021000066368
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author Revell, Matthew P.
Deshmukh, Neeta
Grimer, Robert J.
Carter, Simon R.
Tillman, Roger M.
author_facet Revell, Matthew P.
Deshmukh, Neeta
Grimer, Robert J.
Carter, Simon R.
Tillman, Roger M.
author_sort Revell, Matthew P.
collection PubMed
description Purpose: Periosteal osteosarcomas are rare cartilage-rich bone tumours characterized by a juxtacortical eccentric position and are normally regarded oncologically as of intermediate to high grade.Their low incidence is mirrored by a small number of reported cases in the world literature. While there is general agreement that wide surgical excision is required, there is a paucity of evidence regarding adjuvant therapy. Previous reports have not indicated any consistent approach to this to allow appraisal. Patients and methods: We report 17 cases treated at our centre over 16 years. Our policy was to use chemotherapy when the tumour showed any features of high grade. Results: To date, no deaths have resulted from recurrence or metastasis of the tumour although there have been two deaths from other causes. Discussion: Comparison of survival with existing studies is made to draw conclusions regarding future treatment of this condition in terms of surgical and adjuvant approaches.
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spelling pubmed-23954952008-06-02 Periosteal Osteosarcoma: A Review of 17 Cases with Mean Follow-up of 52 Months Revell, Matthew P. Deshmukh, Neeta Grimer, Robert J. Carter, Simon R. Tillman, Roger M. Sarcoma Research Article Purpose: Periosteal osteosarcomas are rare cartilage-rich bone tumours characterized by a juxtacortical eccentric position and are normally regarded oncologically as of intermediate to high grade.Their low incidence is mirrored by a small number of reported cases in the world literature. While there is general agreement that wide surgical excision is required, there is a paucity of evidence regarding adjuvant therapy. Previous reports have not indicated any consistent approach to this to allow appraisal. Patients and methods: We report 17 cases treated at our centre over 16 years. Our policy was to use chemotherapy when the tumour showed any features of high grade. Results: To date, no deaths have resulted from recurrence or metastasis of the tumour although there have been two deaths from other causes. Discussion: Comparison of survival with existing studies is made to draw conclusions regarding future treatment of this condition in terms of surgical and adjuvant approaches. Hindawi Publishing Corporation 2002-12 /pmc/articles/PMC2395495/ /pubmed/18521348 http://dx.doi.org/10.1080/1357714021000066368 Text en Copyright © 2002 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Revell, Matthew P.
Deshmukh, Neeta
Grimer, Robert J.
Carter, Simon R.
Tillman, Roger M.
Periosteal Osteosarcoma: A Review of 17 Cases with Mean Follow-up of 52 Months
title Periosteal Osteosarcoma: A Review of 17 Cases with Mean Follow-up of 52 Months
title_full Periosteal Osteosarcoma: A Review of 17 Cases with Mean Follow-up of 52 Months
title_fullStr Periosteal Osteosarcoma: A Review of 17 Cases with Mean Follow-up of 52 Months
title_full_unstemmed Periosteal Osteosarcoma: A Review of 17 Cases with Mean Follow-up of 52 Months
title_short Periosteal Osteosarcoma: A Review of 17 Cases with Mean Follow-up of 52 Months
title_sort periosteal osteosarcoma: a review of 17 cases with mean follow-up of 52 months
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395495/
https://www.ncbi.nlm.nih.gov/pubmed/18521348
http://dx.doi.org/10.1080/1357714021000066368
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AT cartersimonr periostealosteosarcomaareviewof17caseswithmeanfollowupof52months
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