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Periosteal Osteosarcoma: A Review of 17 Cases with Mean Follow-up of 52 Months
Purpose: Periosteal osteosarcomas are rare cartilage-rich bone tumours characterized by a juxtacortical eccentric position and are normally regarded oncologically as of intermediate to high grade.Their low incidence is mirrored by a small number of reported cases in the world literature. While there...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2002
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395495/ https://www.ncbi.nlm.nih.gov/pubmed/18521348 http://dx.doi.org/10.1080/1357714021000066368 |
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author | Revell, Matthew P. Deshmukh, Neeta Grimer, Robert J. Carter, Simon R. Tillman, Roger M. |
author_facet | Revell, Matthew P. Deshmukh, Neeta Grimer, Robert J. Carter, Simon R. Tillman, Roger M. |
author_sort | Revell, Matthew P. |
collection | PubMed |
description | Purpose: Periosteal osteosarcomas are rare cartilage-rich bone tumours characterized by a juxtacortical eccentric position and are normally regarded oncologically as of intermediate to high grade.Their low incidence is mirrored by a small number of reported cases in the world literature. While there is general agreement that wide surgical excision is required, there is a paucity of evidence regarding adjuvant therapy. Previous reports have not indicated any consistent approach to this to allow appraisal. Patients and methods: We report 17 cases treated at our centre over 16 years. Our policy was to use chemotherapy when the tumour showed any features of high grade. Results: To date, no deaths have resulted from recurrence or metastasis of the tumour although there have been two deaths from other causes. Discussion: Comparison of survival with existing studies is made to draw conclusions regarding future treatment of this condition in terms of surgical and adjuvant approaches. |
format | Text |
id | pubmed-2395495 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2002 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-23954952008-06-02 Periosteal Osteosarcoma: A Review of 17 Cases with Mean Follow-up of 52 Months Revell, Matthew P. Deshmukh, Neeta Grimer, Robert J. Carter, Simon R. Tillman, Roger M. Sarcoma Research Article Purpose: Periosteal osteosarcomas are rare cartilage-rich bone tumours characterized by a juxtacortical eccentric position and are normally regarded oncologically as of intermediate to high grade.Their low incidence is mirrored by a small number of reported cases in the world literature. While there is general agreement that wide surgical excision is required, there is a paucity of evidence regarding adjuvant therapy. Previous reports have not indicated any consistent approach to this to allow appraisal. Patients and methods: We report 17 cases treated at our centre over 16 years. Our policy was to use chemotherapy when the tumour showed any features of high grade. Results: To date, no deaths have resulted from recurrence or metastasis of the tumour although there have been two deaths from other causes. Discussion: Comparison of survival with existing studies is made to draw conclusions regarding future treatment of this condition in terms of surgical and adjuvant approaches. Hindawi Publishing Corporation 2002-12 /pmc/articles/PMC2395495/ /pubmed/18521348 http://dx.doi.org/10.1080/1357714021000066368 Text en Copyright © 2002 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Revell, Matthew P. Deshmukh, Neeta Grimer, Robert J. Carter, Simon R. Tillman, Roger M. Periosteal Osteosarcoma: A Review of 17 Cases with Mean Follow-up of 52 Months |
title | Periosteal Osteosarcoma: A Review of 17 Cases with Mean Follow-up
of 52 Months |
title_full | Periosteal Osteosarcoma: A Review of 17 Cases with Mean Follow-up
of 52 Months |
title_fullStr | Periosteal Osteosarcoma: A Review of 17 Cases with Mean Follow-up
of 52 Months |
title_full_unstemmed | Periosteal Osteosarcoma: A Review of 17 Cases with Mean Follow-up
of 52 Months |
title_short | Periosteal Osteosarcoma: A Review of 17 Cases with Mean Follow-up
of 52 Months |
title_sort | periosteal osteosarcoma: a review of 17 cases with mean follow-up
of 52 months |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395495/ https://www.ncbi.nlm.nih.gov/pubmed/18521348 http://dx.doi.org/10.1080/1357714021000066368 |
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