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Ten-Year Follow-Up of a Patient with Metastatic Ewing's Sarcoma of the Pelvis

Patient: We report a 32-year-old women with a pelvic Ewing's sarcoma, who developed skeletal metastases within 20 months of diagnosis but following treatment remains disease-free at 10 years. Discussion: Ewing's sarcoma is a highly malignant tumour of bone. Presentation of a pelvic tumour...

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Detalles Bibliográficos
Autores principales: Ashford, Robert U., McCloskey, Eugene V., Purohit, O. Prakash, Ingram, Christine E., Grimer, Robert J., Coleman, Robert E.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395498/
https://www.ncbi.nlm.nih.gov/pubmed/18521349
http://dx.doi.org/10.1080/1357714021000022140
Descripción
Sumario:Patient: We report a 32-year-old women with a pelvic Ewing's sarcoma, who developed skeletal metastases within 20 months of diagnosis but following treatment remains disease-free at 10 years. Discussion: Ewing's sarcoma is a highly malignant tumour of bone. Presentation of a pelvic tumour over the age of 30 years is extremely rare and associated with a poor prognosis. Early recurrence is also associated with an extremely grave prognosis. In our patient there was little or no response to salvage chemotherapy, but, against the odds, remission was induced with pamidronate and palliative radiotherapy to some but not all sites of disease.This remission has been maintained without additional therapy for a further 5 years.