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Ten-Year Follow-Up of a Patient with Metastatic Ewing's Sarcoma of the Pelvis

Patient: We report a 32-year-old women with a pelvic Ewing's sarcoma, who developed skeletal metastases within 20 months of diagnosis but following treatment remains disease-free at 10 years. Discussion: Ewing's sarcoma is a highly malignant tumour of bone. Presentation of a pelvic tumour...

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Detalles Bibliográficos
Autores principales: Ashford, Robert U., McCloskey, Eugene V., Purohit, O. Prakash, Ingram, Christine E., Grimer, Robert J., Coleman, Robert E.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395498/
https://www.ncbi.nlm.nih.gov/pubmed/18521349
http://dx.doi.org/10.1080/1357714021000022140
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author Ashford, Robert U.
McCloskey, Eugene V.
Purohit, O. Prakash
Ingram, Christine E.
Grimer, Robert J.
Coleman, Robert E.
author_facet Ashford, Robert U.
McCloskey, Eugene V.
Purohit, O. Prakash
Ingram, Christine E.
Grimer, Robert J.
Coleman, Robert E.
author_sort Ashford, Robert U.
collection PubMed
description Patient: We report a 32-year-old women with a pelvic Ewing's sarcoma, who developed skeletal metastases within 20 months of diagnosis but following treatment remains disease-free at 10 years. Discussion: Ewing's sarcoma is a highly malignant tumour of bone. Presentation of a pelvic tumour over the age of 30 years is extremely rare and associated with a poor prognosis. Early recurrence is also associated with an extremely grave prognosis. In our patient there was little or no response to salvage chemotherapy, but, against the odds, remission was induced with pamidronate and palliative radiotherapy to some but not all sites of disease.This remission has been maintained without additional therapy for a further 5 years.
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spelling pubmed-23954982008-06-02 Ten-Year Follow-Up of a Patient with Metastatic Ewing's Sarcoma of the Pelvis Ashford, Robert U. McCloskey, Eugene V. Purohit, O. Prakash Ingram, Christine E. Grimer, Robert J. Coleman, Robert E. Sarcoma Research Article Patient: We report a 32-year-old women with a pelvic Ewing's sarcoma, who developed skeletal metastases within 20 months of diagnosis but following treatment remains disease-free at 10 years. Discussion: Ewing's sarcoma is a highly malignant tumour of bone. Presentation of a pelvic tumour over the age of 30 years is extremely rare and associated with a poor prognosis. Early recurrence is also associated with an extremely grave prognosis. In our patient there was little or no response to salvage chemotherapy, but, against the odds, remission was induced with pamidronate and palliative radiotherapy to some but not all sites of disease.This remission has been maintained without additional therapy for a further 5 years. Hindawi Publishing Corporation 2002-12 /pmc/articles/PMC2395498/ /pubmed/18521349 http://dx.doi.org/10.1080/1357714021000022140 Text en Copyright © 2002 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Ashford, Robert U.
McCloskey, Eugene V.
Purohit, O. Prakash
Ingram, Christine E.
Grimer, Robert J.
Coleman, Robert E.
Ten-Year Follow-Up of a Patient with Metastatic Ewing's Sarcoma of the Pelvis
title Ten-Year Follow-Up of a Patient with Metastatic Ewing's Sarcoma of the Pelvis
title_full Ten-Year Follow-Up of a Patient with Metastatic Ewing's Sarcoma of the Pelvis
title_fullStr Ten-Year Follow-Up of a Patient with Metastatic Ewing's Sarcoma of the Pelvis
title_full_unstemmed Ten-Year Follow-Up of a Patient with Metastatic Ewing's Sarcoma of the Pelvis
title_short Ten-Year Follow-Up of a Patient with Metastatic Ewing's Sarcoma of the Pelvis
title_sort ten-year follow-up of a patient with metastatic ewing's sarcoma of the pelvis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395498/
https://www.ncbi.nlm.nih.gov/pubmed/18521349
http://dx.doi.org/10.1080/1357714021000022140
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