Cargando…
Ten-Year Follow-Up of a Patient with Metastatic Ewing's Sarcoma of the Pelvis
Patient: We report a 32-year-old women with a pelvic Ewing's sarcoma, who developed skeletal metastases within 20 months of diagnosis but following treatment remains disease-free at 10 years. Discussion: Ewing's sarcoma is a highly malignant tumour of bone. Presentation of a pelvic tumour...
Autores principales: | , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2002
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395498/ https://www.ncbi.nlm.nih.gov/pubmed/18521349 http://dx.doi.org/10.1080/1357714021000022140 |
_version_ | 1782155520417726464 |
---|---|
author | Ashford, Robert U. McCloskey, Eugene V. Purohit, O. Prakash Ingram, Christine E. Grimer, Robert J. Coleman, Robert E. |
author_facet | Ashford, Robert U. McCloskey, Eugene V. Purohit, O. Prakash Ingram, Christine E. Grimer, Robert J. Coleman, Robert E. |
author_sort | Ashford, Robert U. |
collection | PubMed |
description | Patient: We report a 32-year-old women with a pelvic Ewing's sarcoma, who developed skeletal metastases within 20 months of diagnosis but following treatment remains disease-free at 10 years. Discussion: Ewing's sarcoma is a highly malignant tumour of bone. Presentation of a pelvic tumour over the age of 30 years is extremely rare and associated with a poor prognosis. Early recurrence is also associated with an extremely grave prognosis. In our patient there was little or no response to salvage chemotherapy, but, against the odds, remission was induced with pamidronate and palliative radiotherapy to some but not all sites of disease.This remission has been maintained without additional therapy for a further 5 years. |
format | Text |
id | pubmed-2395498 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2002 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-23954982008-06-02 Ten-Year Follow-Up of a Patient with Metastatic Ewing's Sarcoma of the Pelvis Ashford, Robert U. McCloskey, Eugene V. Purohit, O. Prakash Ingram, Christine E. Grimer, Robert J. Coleman, Robert E. Sarcoma Research Article Patient: We report a 32-year-old women with a pelvic Ewing's sarcoma, who developed skeletal metastases within 20 months of diagnosis but following treatment remains disease-free at 10 years. Discussion: Ewing's sarcoma is a highly malignant tumour of bone. Presentation of a pelvic tumour over the age of 30 years is extremely rare and associated with a poor prognosis. Early recurrence is also associated with an extremely grave prognosis. In our patient there was little or no response to salvage chemotherapy, but, against the odds, remission was induced with pamidronate and palliative radiotherapy to some but not all sites of disease.This remission has been maintained without additional therapy for a further 5 years. Hindawi Publishing Corporation 2002-12 /pmc/articles/PMC2395498/ /pubmed/18521349 http://dx.doi.org/10.1080/1357714021000022140 Text en Copyright © 2002 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Ashford, Robert U. McCloskey, Eugene V. Purohit, O. Prakash Ingram, Christine E. Grimer, Robert J. Coleman, Robert E. Ten-Year Follow-Up of a Patient with Metastatic Ewing's Sarcoma of the Pelvis |
title | Ten-Year Follow-Up of a Patient with Metastatic Ewing's Sarcoma
of the Pelvis |
title_full | Ten-Year Follow-Up of a Patient with Metastatic Ewing's Sarcoma
of the Pelvis |
title_fullStr | Ten-Year Follow-Up of a Patient with Metastatic Ewing's Sarcoma
of the Pelvis |
title_full_unstemmed | Ten-Year Follow-Up of a Patient with Metastatic Ewing's Sarcoma
of the Pelvis |
title_short | Ten-Year Follow-Up of a Patient with Metastatic Ewing's Sarcoma
of the Pelvis |
title_sort | ten-year follow-up of a patient with metastatic ewing's sarcoma
of the pelvis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395498/ https://www.ncbi.nlm.nih.gov/pubmed/18521349 http://dx.doi.org/10.1080/1357714021000022140 |
work_keys_str_mv | AT ashfordrobertu tenyearfollowupofapatientwithmetastaticewingssarcomaofthepelvis AT mccloskeyeugenev tenyearfollowupofapatientwithmetastaticewingssarcomaofthepelvis AT purohitoprakash tenyearfollowupofapatientwithmetastaticewingssarcomaofthepelvis AT ingramchristinee tenyearfollowupofapatientwithmetastaticewingssarcomaofthepelvis AT grimerrobertj tenyearfollowupofapatientwithmetastaticewingssarcomaofthepelvis AT colemanroberte tenyearfollowupofapatientwithmetastaticewingssarcomaofthepelvis |