Metastatic Secondary Fibrosarcoma of Bone Responsive to Repeated Courses of Ifosfamide and Associated With Hypoglycemia

We present a case of a 40-year-old man with secondary fibrosarcoma of bone, arising from a non-ossifying fibroma. He subsequently developed metastatic disease that responded to four successive chemotherapy courses, the last three using the same dose/schedule of single agent ifosfamide. Eventual rapi...

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Detalles Bibliográficos
Autores principales: Bouttell, Elaine S., Rodger, N. Wilson, Bramwell, Vivien H. C.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395515/
https://www.ncbi.nlm.nih.gov/pubmed/18521374
http://dx.doi.org/10.1080/13577140310001607329
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author Bouttell, Elaine S.
Rodger, N. Wilson
Bramwell, Vivien H. C.
author_facet Bouttell, Elaine S.
Rodger, N. Wilson
Bramwell, Vivien H. C.
author_sort Bouttell, Elaine S.
collection PubMed
description We present a case of a 40-year-old man with secondary fibrosarcoma of bone, arising from a non-ossifying fibroma. He subsequently developed metastatic disease that responded to four successive chemotherapy courses, the last three using the same dose/schedule of single agent ifosfamide. Eventual rapid progression of a huge intra-abdominal mass was associated with the syndrome of extrapancreatic tumour hypoglycemia (EPTH). The clinicopathological behaviour of fibrosarcoma of bone, and the mechanism of EPTH are discussed.
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spelling pubmed-23955152008-06-02 Metastatic Secondary Fibrosarcoma of Bone Responsive to Repeated Courses of Ifosfamide and Associated With Hypoglycemia Bouttell, Elaine S. Rodger, N. Wilson Bramwell, Vivien H. C. Sarcoma Research Article We present a case of a 40-year-old man with secondary fibrosarcoma of bone, arising from a non-ossifying fibroma. He subsequently developed metastatic disease that responded to four successive chemotherapy courses, the last three using the same dose/schedule of single agent ifosfamide. Eventual rapid progression of a huge intra-abdominal mass was associated with the syndrome of extrapancreatic tumour hypoglycemia (EPTH). The clinicopathological behaviour of fibrosarcoma of bone, and the mechanism of EPTH are discussed. Hindawi Publishing Corporation 2003-06 /pmc/articles/PMC2395515/ /pubmed/18521374 http://dx.doi.org/10.1080/13577140310001607329 Text en Copyright © 2003 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Bouttell, Elaine S.
Rodger, N. Wilson
Bramwell, Vivien H. C.
Metastatic Secondary Fibrosarcoma of Bone Responsive to Repeated Courses of Ifosfamide and Associated With Hypoglycemia
title Metastatic Secondary Fibrosarcoma of Bone Responsive to Repeated Courses of Ifosfamide and Associated With Hypoglycemia
title_full Metastatic Secondary Fibrosarcoma of Bone Responsive to Repeated Courses of Ifosfamide and Associated With Hypoglycemia
title_fullStr Metastatic Secondary Fibrosarcoma of Bone Responsive to Repeated Courses of Ifosfamide and Associated With Hypoglycemia
title_full_unstemmed Metastatic Secondary Fibrosarcoma of Bone Responsive to Repeated Courses of Ifosfamide and Associated With Hypoglycemia
title_short Metastatic Secondary Fibrosarcoma of Bone Responsive to Repeated Courses of Ifosfamide and Associated With Hypoglycemia
title_sort metastatic secondary fibrosarcoma of bone responsive to repeated courses of ifosfamide and associated with hypoglycemia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395515/
https://www.ncbi.nlm.nih.gov/pubmed/18521374
http://dx.doi.org/10.1080/13577140310001607329
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AT rodgernwilson metastaticsecondaryfibrosarcomaofboneresponsivetorepeatedcoursesofifosfamideandassociatedwithhypoglycemia
AT bramwellvivienhc metastaticsecondaryfibrosarcomaofboneresponsivetorepeatedcoursesofifosfamideandassociatedwithhypoglycemia

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