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A Radiotherapy Technique to Improve Dose Homogeneity Around Bone Prostheses
Purpose. Following limb conserving surgery for bone or soft tissue sarcoma, patients may require post-operative radiotherapy to minimise the risk of local recurrence. In such circumstances the metal prosthesis reduces the dose in its shadow by approximately 10% when using opposed fields. We describe...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395598/ https://www.ncbi.nlm.nih.gov/pubmed/18521392 http://dx.doi.org/10.1080/13577140410001679248 |
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author | Williams, M. V. Burnet, N. G. Sherwin, E. Kestelman, R. Geater, A. R. Thomas, S. J. Wilson, C. B. |
author_facet | Williams, M. V. Burnet, N. G. Sherwin, E. Kestelman, R. Geater, A. R. Thomas, S. J. Wilson, C. B. |
author_sort | Williams, M. V. |
collection | PubMed |
description | Purpose. Following limb conserving surgery for bone or soft tissue sarcoma, patients may require post-operative radiotherapy to minimise the risk of local recurrence. In such circumstances the metal prosthesis reduces the dose in its shadow by approximately 10% when using opposed fields. We describe a technique to boost the underdosed area to overcome this problem. Patients or subjects. Seven sequential patients presenting between 1995 and 2001 had their treatment individualised because they had metal prosthesis in the treatment volume. Methods. To improve the target dose homogeneity we used a custom-made keyhole cutout to boost the area in the shadow of the prosthesis. The degree of attenuation caused by the metal prosthesis was estimated and a boost dose calculated. Exit thermoluminescent dosimetry (TLD) was used to confirm the estimates made. Results and discussion. Variation between patients was seen, demonstrating the need for exit TLD to individualise the treatment plan. The use of a boost field provides a method to overcome under-dosage in the shadow of a metal prosthesis. It improves dose homogeneity throughout the target volume and ensures adequate dose intensity around the prosthesis, the site most at risk of local recurrence. |
format | Text |
id | pubmed-2395598 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2004 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-23955982008-06-02 A Radiotherapy Technique to Improve Dose Homogeneity Around Bone Prostheses Williams, M. V. Burnet, N. G. Sherwin, E. Kestelman, R. Geater, A. R. Thomas, S. J. Wilson, C. B. Sarcoma Research Article Purpose. Following limb conserving surgery for bone or soft tissue sarcoma, patients may require post-operative radiotherapy to minimise the risk of local recurrence. In such circumstances the metal prosthesis reduces the dose in its shadow by approximately 10% when using opposed fields. We describe a technique to boost the underdosed area to overcome this problem. Patients or subjects. Seven sequential patients presenting between 1995 and 2001 had their treatment individualised because they had metal prosthesis in the treatment volume. Methods. To improve the target dose homogeneity we used a custom-made keyhole cutout to boost the area in the shadow of the prosthesis. The degree of attenuation caused by the metal prosthesis was estimated and a boost dose calculated. Exit thermoluminescent dosimetry (TLD) was used to confirm the estimates made. Results and discussion. Variation between patients was seen, demonstrating the need for exit TLD to individualise the treatment plan. The use of a boost field provides a method to overcome under-dosage in the shadow of a metal prosthesis. It improves dose homogeneity throughout the target volume and ensures adequate dose intensity around the prosthesis, the site most at risk of local recurrence. Hindawi Publishing Corporation 2004-03 /pmc/articles/PMC2395598/ /pubmed/18521392 http://dx.doi.org/10.1080/13577140410001679248 Text en Copyright © 2004 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Williams, M. V. Burnet, N. G. Sherwin, E. Kestelman, R. Geater, A. R. Thomas, S. J. Wilson, C. B. A Radiotherapy Technique to Improve Dose Homogeneity Around Bone Prostheses |
title | A Radiotherapy Technique to Improve Dose Homogeneity Around Bone Prostheses |
title_full | A Radiotherapy Technique to Improve Dose Homogeneity Around Bone Prostheses |
title_fullStr | A Radiotherapy Technique to Improve Dose Homogeneity Around Bone Prostheses |
title_full_unstemmed | A Radiotherapy Technique to Improve Dose Homogeneity Around Bone Prostheses |
title_short | A Radiotherapy Technique to Improve Dose Homogeneity Around Bone Prostheses |
title_sort | radiotherapy technique to improve dose homogeneity around bone prostheses |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395598/ https://www.ncbi.nlm.nih.gov/pubmed/18521392 http://dx.doi.org/10.1080/13577140410001679248 |
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