Phase II Trial of Dolastatin-10, a Novel Anti-Tubulin Agent, in Metastatic Soft Tissue Sarcomas

Patients: Soft tissue sarcomas are uncommon malignancies with few therapeutic options for recurrent or metastatic disease. Dolastatin-10 (Dol-10) is a pentapeptide anti-microtubule agent that binds to tubulin sites distinct from vinca alkaloids. Based on the novel mechanism of action, limited activi...

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Detalles Bibliográficos
Autores principales: von Mehren, M., Balcerzak, S. P., Kraft, A. S., Edmonson, J. H., Okuno, S. H., Davey, M., Mclaughlin, S., Beard, M. T., Rogatko, A.
Formato: Texto
Lenguaje:English
Publicado: Sarcoma 2004
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395616/
https://www.ncbi.nlm.nih.gov/pubmed/18521404
http://dx.doi.org/10.1155/2004/924913

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