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RU486 did not exacerbate cytokine release in mice challenged with LPS nor in db/db mice

BACKGROUND: Glucocorticoids down-regulate cytokine synthesis and suppress inflammatory responses. The glucocorticoid receptor (GR) antagonist RU486 may exacerbate the inflammatory response, and concerns over this exacerbation have limited the development and clinical use of GR antagonists in the tre...

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Detalles Bibliográficos
Autores principales:	Yang, Baichun, Trump, Ryan P, Shen, Ying, McNulty, Judi A, Clifton, Lisa G, Stimpson, Stephen A, Lin, Peiyuan, Pahel, Greg L
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396158/ https://www.ncbi.nlm.nih.gov/pubmed/18474108 http://dx.doi.org/10.1186/1471-2210-8-7

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