Mismatched dNTP incorporation by DNA polymerase β does not proceed via globally different conformational pathways(†)

Understanding how DNA polymerases control fidelity requires elucidation of the mechanisms of matched and mismatched dNTP incorporations. Little is known about the latter because mismatched complexes do not crystallize readily. In this report, we employed small-angle X-ray scattering (SAXS) and struc...

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Detalles Bibliográficos
Autores principales: Tang, Kuo-Hsiang, Niebuhr, Marc, Tung, Chang-Shung, Chan, Hsiu-chien, Chou, Chia-Cheng, Tsai, Ming-Daw
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396427/
https://www.ncbi.nlm.nih.gov/pubmed/18385153
http://dx.doi.org/10.1093/nar/gkn138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396427/
https://www.ncbi.nlm.nih.gov/pubmed/18385153
http://dx.doi.org/10.1093/nar/gkn138

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