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Mismatched dNTP incorporation by DNA polymerase β does not proceed via globally different conformational pathways(†)
Understanding how DNA polymerases control fidelity requires elucidation of the mechanisms of matched and mismatched dNTP incorporations. Little is known about the latter because mismatched complexes do not crystallize readily. In this report, we employed small-angle X-ray scattering (SAXS) and struc...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396427/ https://www.ncbi.nlm.nih.gov/pubmed/18385153 http://dx.doi.org/10.1093/nar/gkn138 |