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Analysis of siRNA specificity on targets with double-nucleotide mismatches

Although RNA interference as a tool for gene knockdown is a great promise for future applications, the specificity of small interfering RNA (siRNA)-mediated gene silencing needs to be thoroughly investigated. Most research regarding siRNA specificity has involved analysis of affected off-target gene...

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Detalles Bibliográficos
Autores principales:	Dahlgren, Cecilia, Zhang, Hong-Yan, Du, Quan, Grahn, Maria, Norstedt, Gunnar, Wahlestedt, Claes, Liang, Zicai
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396434/ https://www.ncbi.nlm.nih.gov/pubmed/18420656 http://dx.doi.org/10.1093/nar/gkn190

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