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CSMET: Comparative Genomic Motif Detection via Multi-Resolution Phylogenetic Shadowing

Functional turnover of transcription factor binding sites (TFBSs), such as whole-motif loss or gain, are common events during genome evolution. Conventional probabilistic phylogenetic shadowing methods model the evolution of genomes only at nucleotide level, and lack the ability to capture the evolu...

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Detalles Bibliográficos
Autores principales: Ray, Pradipta, Shringarpure, Suyash, Kolar, Mladen, Xing, Eric P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396503/
https://www.ncbi.nlm.nih.gov/pubmed/18535663
http://dx.doi.org/10.1371/journal.pcbi.1000090