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Cancer patterns among children of Turkish descent in Germany: A study at the German Childhood Cancer Registry

BACKGROUND: Cancer risks of migrants might differ from risks of the indigenous population due to differences in socioeconomic status, life style, or genetic factors. The aim of this study was to investigate cancer patterns among children of Turkish descent in Germany. METHODS: We identified cases wi...

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Detalles Bibliográficos
Autores principales: Spallek, Jacob, Spix, Claudia, Zeeb, Hajo, Kaatsch, Peter, Razum, Oliver
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396623/
https://www.ncbi.nlm.nih.gov/pubmed/18462495
http://dx.doi.org/10.1186/1471-2458-8-152
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author Spallek, Jacob
Spix, Claudia
Zeeb, Hajo
Kaatsch, Peter
Razum, Oliver
author_facet Spallek, Jacob
Spix, Claudia
Zeeb, Hajo
Kaatsch, Peter
Razum, Oliver
author_sort Spallek, Jacob
collection PubMed
description BACKGROUND: Cancer risks of migrants might differ from risks of the indigenous population due to differences in socioeconomic status, life style, or genetic factors. The aim of this study was to investigate cancer patterns among children of Turkish descent in Germany. METHODS: We identified cases with Turkish names (as a proxy of Turkish descent) among the 37,259 cases of childhood cancer registered in the German Childhood Cancer Registry (GCCR) during 1980–2005. As it is not possible to obtain reference population data for children of Turkish descent, the distribution of cancer diagnoses was compared between cases of Turkish descent and all remaining (mainly German) cases in the registry, using proportional cancer incidence ratios (PCIRs). RESULTS: The overall distribution of cancer diagnoses was similar in the two groups. The PCIRs in three diagnosis groups were increased for cases of Turkish descent: acute non-lymphocytic leukaemia (PCIR 1.23; CI (95%) 1.02–1.47), Hodgkin's disease (1.34; 1.13–1.59) and Non-Hodgkin/Burkitt lymphoma (1.19; 1.02–1.39). Age, sex, and period of diagnosis showed no influence on the distribution of diagnoses. CONCLUSION: No major differences were found in cancer patterns among cases of Turkish descent compared to all other cases in the GCCR. Slightly higher proportions of systemic malignant diseases indicate that analytical studies involving migrants may help investigating the causes of such cancers.
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spelling pubmed-23966232008-05-28 Cancer patterns among children of Turkish descent in Germany: A study at the German Childhood Cancer Registry Spallek, Jacob Spix, Claudia Zeeb, Hajo Kaatsch, Peter Razum, Oliver BMC Public Health Research Article BACKGROUND: Cancer risks of migrants might differ from risks of the indigenous population due to differences in socioeconomic status, life style, or genetic factors. The aim of this study was to investigate cancer patterns among children of Turkish descent in Germany. METHODS: We identified cases with Turkish names (as a proxy of Turkish descent) among the 37,259 cases of childhood cancer registered in the German Childhood Cancer Registry (GCCR) during 1980–2005. As it is not possible to obtain reference population data for children of Turkish descent, the distribution of cancer diagnoses was compared between cases of Turkish descent and all remaining (mainly German) cases in the registry, using proportional cancer incidence ratios (PCIRs). RESULTS: The overall distribution of cancer diagnoses was similar in the two groups. The PCIRs in three diagnosis groups were increased for cases of Turkish descent: acute non-lymphocytic leukaemia (PCIR 1.23; CI (95%) 1.02–1.47), Hodgkin's disease (1.34; 1.13–1.59) and Non-Hodgkin/Burkitt lymphoma (1.19; 1.02–1.39). Age, sex, and period of diagnosis showed no influence on the distribution of diagnoses. CONCLUSION: No major differences were found in cancer patterns among cases of Turkish descent compared to all other cases in the GCCR. Slightly higher proportions of systemic malignant diseases indicate that analytical studies involving migrants may help investigating the causes of such cancers. BioMed Central 2008-05-07 /pmc/articles/PMC2396623/ /pubmed/18462495 http://dx.doi.org/10.1186/1471-2458-8-152 Text en Copyright © 2008 Spallek et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Spallek, Jacob
Spix, Claudia
Zeeb, Hajo
Kaatsch, Peter
Razum, Oliver
Cancer patterns among children of Turkish descent in Germany: A study at the German Childhood Cancer Registry
title Cancer patterns among children of Turkish descent in Germany: A study at the German Childhood Cancer Registry
title_full Cancer patterns among children of Turkish descent in Germany: A study at the German Childhood Cancer Registry
title_fullStr Cancer patterns among children of Turkish descent in Germany: A study at the German Childhood Cancer Registry
title_full_unstemmed Cancer patterns among children of Turkish descent in Germany: A study at the German Childhood Cancer Registry
title_short Cancer patterns among children of Turkish descent in Germany: A study at the German Childhood Cancer Registry
title_sort cancer patterns among children of turkish descent in germany: a study at the german childhood cancer registry
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396623/
https://www.ncbi.nlm.nih.gov/pubmed/18462495
http://dx.doi.org/10.1186/1471-2458-8-152
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