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Selection dramatically reduces effective population size in HIV-1 infection
BACKGROUND: In HIV-1 evolution, a 100–100,000 fold discrepancy between census size and effective population size (N(e)) has been noted. Although it is well known that selection can reduce N(e), high in vivo mutation and recombination rates complicate attempts to quantify the effects of selection on...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396635/ https://www.ncbi.nlm.nih.gov/pubmed/18454872 http://dx.doi.org/10.1186/1471-2148-8-133 |