Desmin mediates TNF-α–induced aggregate formation and intercalated disk reorganization in heart failure

We explored the involvement of the muscle-specific intermediate filament protein desmin in the model of tumor necrosis factor α (TNF-α)–induced cardiomyopathy. We demonstrate that in mice overexpressing TNF-α in the heart (α–myosin heavy chain promoter-driven secretable TNF-α [MHCsTNF]), desmin is m...

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Detalles Bibliográficos
Autores principales: Panagopoulou, Panagiota, Davos, Constantinos H., Milner, Derek J., Varela, Emily, Cameron, JoAnn, Mann, Douglas L., Capetanaki, Yassemi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396798/
https://www.ncbi.nlm.nih.gov/pubmed/18519735
http://dx.doi.org/10.1083/jcb.200710049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396798/
https://www.ncbi.nlm.nih.gov/pubmed/18519735
http://dx.doi.org/10.1083/jcb.200710049

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