Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than Hereditary Non Polyposis Colorectal Cancer cohorts

OBJECTIVE: To determine and compare the prevalence of MSH6 (a mismatch repair gene) mutations in a cohort of families with Hereditary Non-Polyposis Colorectal Cancer (HNPCC), and in an unselected cohort of endometrial cancer patients (EC). DESIGN: Two patient cohorts participated in the study. A coh...

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Detalles Bibliográficos
Autores principales: Devlin, Lisa A, Graham, Colin A, Price, John H, Morrison, Patrick J
Formato: Texto
Lenguaje:English
Publicado: The Ulster Medical Society 2008
Materias:
Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2397009/
https://www.ncbi.nlm.nih.gov/pubmed/18269114

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