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Refined study of the interaction between HIV-1 p6 late domain and ALIX

The interaction between the HIV-1 p6 late budding domain and ALIX, a class E vacuolar protein sorting factor, was explored by using the yeast two-hybrid approach. We refined the ALIX binding site of p6 as being the leucine triplet repeat sequence (Lxx)(4 )(LYPLTSLRSLFG). Intriguingly, the deletion o...

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Detalles Bibliográficos
Autores principales: Lazert, Carine, Chazal, Nathalie, Briant, Laurence, Gerlier, Denis, Cortay, Jean-Claude
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2397435/
https://www.ncbi.nlm.nih.gov/pubmed/18477395
http://dx.doi.org/10.1186/1742-4690-5-39