Serum Alpha-Fetoprotein Predicts Treatment Outcome in Chronic Hepatitis C Patients Regardless of HCV Genotype

We examined the association between serum alpha-fetoprotein (AFP) level and sustained virological response (SVR) in 93 chronic hepatitis C patients. The SVR rate was much higher among patients with serum AFP levels below rather than above the median value (5.7 ng/ml) (58.7% and 19.2%, respectively;...

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Detalles Bibliográficos
Autores principales: Abdoul, Hendy, Mallet, Vincent, Pol, Stanislas, Fontanet, Arnaud
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2398780/
https://www.ncbi.nlm.nih.gov/pubmed/18545682
http://dx.doi.org/10.1371/journal.pone.0002391
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author Abdoul, Hendy
Mallet, Vincent
Pol, Stanislas
Fontanet, Arnaud
author_facet Abdoul, Hendy
Mallet, Vincent
Pol, Stanislas
Fontanet, Arnaud
author_sort Abdoul, Hendy
collection PubMed
description We examined the association between serum alpha-fetoprotein (AFP) level and sustained virological response (SVR) in 93 chronic hepatitis C patients. The SVR rate was much higher among patients with serum AFP levels below rather than above the median value (5.7 ng/ml) (58.7% and 19.2%, respectively; P<0.0001). Serum AFP should be added to the list of factors predictive of treatment response in chronic hepatitis C.
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spelling pubmed-23987802008-06-11 Serum Alpha-Fetoprotein Predicts Treatment Outcome in Chronic Hepatitis C Patients Regardless of HCV Genotype Abdoul, Hendy Mallet, Vincent Pol, Stanislas Fontanet, Arnaud PLoS One Research Article We examined the association between serum alpha-fetoprotein (AFP) level and sustained virological response (SVR) in 93 chronic hepatitis C patients. The SVR rate was much higher among patients with serum AFP levels below rather than above the median value (5.7 ng/ml) (58.7% and 19.2%, respectively; P<0.0001). Serum AFP should be added to the list of factors predictive of treatment response in chronic hepatitis C. Public Library of Science 2008-06-11 /pmc/articles/PMC2398780/ /pubmed/18545682 http://dx.doi.org/10.1371/journal.pone.0002391 Text en Abdoul et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Abdoul, Hendy
Mallet, Vincent
Pol, Stanislas
Fontanet, Arnaud
Serum Alpha-Fetoprotein Predicts Treatment Outcome in Chronic Hepatitis C Patients Regardless of HCV Genotype
title Serum Alpha-Fetoprotein Predicts Treatment Outcome in Chronic Hepatitis C Patients Regardless of HCV Genotype
title_full Serum Alpha-Fetoprotein Predicts Treatment Outcome in Chronic Hepatitis C Patients Regardless of HCV Genotype
title_fullStr Serum Alpha-Fetoprotein Predicts Treatment Outcome in Chronic Hepatitis C Patients Regardless of HCV Genotype
title_full_unstemmed Serum Alpha-Fetoprotein Predicts Treatment Outcome in Chronic Hepatitis C Patients Regardless of HCV Genotype
title_short Serum Alpha-Fetoprotein Predicts Treatment Outcome in Chronic Hepatitis C Patients Regardless of HCV Genotype
title_sort serum alpha-fetoprotein predicts treatment outcome in chronic hepatitis c patients regardless of hcv genotype
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2398780/
https://www.ncbi.nlm.nih.gov/pubmed/18545682
http://dx.doi.org/10.1371/journal.pone.0002391
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