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The role of protein elongation factor eEF1A2 in ovarian cancer
Frequent gains of chromosome 20q12-13 in ovarian tumors indicate that at least one important oncogene is found at that locus. One of the genes there is EEF1A2, which maps to 20q13.3 and encodes protein elongation factor eEF1A2. This review will focus on recent evidence indicating that EEF1A2 is an i...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2003
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC239897/ https://www.ncbi.nlm.nih.gov/pubmed/14588074 http://dx.doi.org/10.1186/1477-7827-1-69 |
| _version_ | 1782120983481548800 |
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| author | Lee, Jonathan M |
| author_facet | Lee, Jonathan M |
| author_sort | Lee, Jonathan M |
| collection | PubMed |
| description | Frequent gains of chromosome 20q12-13 in ovarian tumors indicate that at least one important oncogene is found at that locus. One of the genes there is EEF1A2, which maps to 20q13.3 and encodes protein elongation factor eEF1A2. This review will focus on recent evidence indicating that EEF1A2 is an important ovarian oncogene and that the protein elongation network can activate tumorigenesis and inhibit apoptosis. |
| format | Text |
| id | pubmed-239897 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2003 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-2398972003-11-04 The role of protein elongation factor eEF1A2 in ovarian cancer Lee, Jonathan M Reprod Biol Endocrinol Review Frequent gains of chromosome 20q12-13 in ovarian tumors indicate that at least one important oncogene is found at that locus. One of the genes there is EEF1A2, which maps to 20q13.3 and encodes protein elongation factor eEF1A2. This review will focus on recent evidence indicating that EEF1A2 is an important ovarian oncogene and that the protein elongation network can activate tumorigenesis and inhibit apoptosis. BioMed Central 2003-10-07 /pmc/articles/PMC239897/ /pubmed/14588074 http://dx.doi.org/10.1186/1477-7827-1-69 Text en Copyright © 2003 Lee; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL. |
| spellingShingle | Review Lee, Jonathan M The role of protein elongation factor eEF1A2 in ovarian cancer |
| title | The role of protein elongation factor eEF1A2 in ovarian cancer |
| title_full | The role of protein elongation factor eEF1A2 in ovarian cancer |
| title_fullStr | The role of protein elongation factor eEF1A2 in ovarian cancer |
| title_full_unstemmed | The role of protein elongation factor eEF1A2 in ovarian cancer |
| title_short | The role of protein elongation factor eEF1A2 in ovarian cancer |
| title_sort | role of protein elongation factor eef1a2 in ovarian cancer |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC239897/ https://www.ncbi.nlm.nih.gov/pubmed/14588074 http://dx.doi.org/10.1186/1477-7827-1-69 |
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