BRCA1/2 mutation screening and LOH analysis of lung adenocarcinoma tissue in a multiple-cancer patient with a strong family history of breast cancer

BACKGROUND: Germline mutations in BRCA1/2 greatly elevate risks of breast and ovarian cancers, but the role of these genes in tumourigenesis of other cancer types is still being investigated. OBJECTIVE: We report on an investigation of BRCA1/2 mutations and their loss of heterozygosity (LOH) in a pa...

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Detalles Bibliográficos
Autores principales: Boettger, Melanie Barbara, Sergi, Consolato, Meyer, Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Short Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC239936/
https://www.ncbi.nlm.nih.gov/pubmed/14583096
http://dx.doi.org/10.1186/1477-3163-2-5

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