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A regulatory variation in OPRK1, the gene encoding the κ-opioid receptor, is associated with alcohol dependence
Variations in OPRK1, which encodes the κ-opioid receptor, are associated with the risk for alcohol dependence. Sequencing DNAs with higher and lower risk haplotypes revealed an insertion/deletion (indel) with a net addition of 830 bp located 1986 bp upstream of the translation start site (1389 bp up...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2405904/ https://www.ncbi.nlm.nih.gov/pubmed/18319328 http://dx.doi.org/10.1093/hmg/ddn068 |