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Further characterization of ADAMTS-13 inactivation by thrombin

Background: The multimeric size and platelet-tethering function of von Willebrand factor (VWF) are modulated by the plasma metalloprotease, a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS-13). In vitro ADAMTS-13 is susceptible to proteolytic inactivation by...

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Detalles Bibliográficos
Autores principales: LAM, J K, CHION, C K N K, ZANARDELLI, S, LANE, D A, CRAWLEY, J T B
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408652/
https://www.ncbi.nlm.nih.gov/pubmed/17355572
http://dx.doi.org/10.1111/j.1538-7836.2007.02514.x

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