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TDP-43 Is Not a Common Cause of Sporadic Amyotrophic Lateral Sclerosis
BACKGROUND: TAR DNA binding protein, encoded by TARDBP, was shown to be a central component of ubiquitin-positive, tau-negative inclusions in frontotemporal lobar degeneration (FTLD-U) and amyotrophic lateral sclerosis (ALS). Recently, mutations in TARDBP have been linked to familial and sporadic AL...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408729/ https://www.ncbi.nlm.nih.gov/pubmed/18545701 http://dx.doi.org/10.1371/journal.pone.0002450 |