p53 codon 72 polymorphism in vulval cancer and vulval intraepithelial neoplasia

p53 codon 72 polymorphism was analysed in UK women with human papillomavirus (HPV)-associated vulval intraepithelial neoplasia and vulval squamous cell carcinoma. Arginine homozygotes were significantly less common in either group compared with controls. We conclude that the arginine polymorphism ma...

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Detalles Bibliográficos
Autores principales: Rosenthal, A N, Ryan, A, Hopster, D, Jacobs, I J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408780/
https://www.ncbi.nlm.nih.gov/pubmed/11044351
http://dx.doi.org/10.1054/bjoc.2000.1419
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author Rosenthal, A N
Ryan, A
Hopster, D
Jacobs, I J
author_facet Rosenthal, A N
Ryan, A
Hopster, D
Jacobs, I J
author_sort Rosenthal, A N
collection PubMed
description p53 codon 72 polymorphism was analysed in UK women with human papillomavirus (HPV)-associated vulval intraepithelial neoplasia and vulval squamous cell carcinoma. Arginine homozygotes were significantly less common in either group compared with controls. We conclude that the arginine polymorphism may confer protection against the development of HPV-associated vulval neoplasia. © 2000 Cancer Research Campaign
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spelling pubmed-24087802009-09-10 p53 codon 72 polymorphism in vulval cancer and vulval intraepithelial neoplasia Rosenthal, A N Ryan, A Hopster, D Jacobs, I J Br J Cancer Short Communication p53 codon 72 polymorphism was analysed in UK women with human papillomavirus (HPV)-associated vulval intraepithelial neoplasia and vulval squamous cell carcinoma. Arginine homozygotes were significantly less common in either group compared with controls. We conclude that the arginine polymorphism may confer protection against the development of HPV-associated vulval neoplasia. © 2000 Cancer Research Campaign Nature Publishing Group 2000-11 2000-10-26 /pmc/articles/PMC2408780/ /pubmed/11044351 http://dx.doi.org/10.1054/bjoc.2000.1419 Text en Copyright © 2000 Cancer Research Campaign https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Short Communication
Rosenthal, A N
Ryan, A
Hopster, D
Jacobs, I J
p53 codon 72 polymorphism in vulval cancer and vulval intraepithelial neoplasia
title p53 codon 72 polymorphism in vulval cancer and vulval intraepithelial neoplasia
title_full p53 codon 72 polymorphism in vulval cancer and vulval intraepithelial neoplasia
title_fullStr p53 codon 72 polymorphism in vulval cancer and vulval intraepithelial neoplasia
title_full_unstemmed p53 codon 72 polymorphism in vulval cancer and vulval intraepithelial neoplasia
title_short p53 codon 72 polymorphism in vulval cancer and vulval intraepithelial neoplasia
title_sort p53 codon 72 polymorphism in vulval cancer and vulval intraepithelial neoplasia
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408780/
https://www.ncbi.nlm.nih.gov/pubmed/11044351
http://dx.doi.org/10.1054/bjoc.2000.1419
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AT hopsterd p53codon72polymorphisminvulvalcancerandvulvalintraepithelialneoplasia
AT jacobsij p53codon72polymorphisminvulvalcancerandvulvalintraepithelialneoplasia

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