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Prevalence of bortezomib-resistant constitutive NF-kappaB activity in mantle cell lymphoma
BACKGROUND: The proteasome inhibitor bortezomib can inhibit activation of the transcription factor NF-κB, a mechanism implicated in its anti-neoplastic effects observed in mantle cell lymphoma (MCL). However, NF-κB can be activated through many distinct mechanisms, including proteasome independent p...
Autores principales: | Yang, David T, Young, Ken H, Kahl, Brad S, Markovina, Stephanie, Miyamoto, Shigeki |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408930/ https://www.ncbi.nlm.nih.gov/pubmed/18489772 http://dx.doi.org/10.1186/1476-4598-7-40 |
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