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Model for the Peptide-Free Conformation of Class II MHC Proteins
BACKGROUND: Major histocompatibility complex proteins are believed to undergo significant conformational changes concomitant with peptide binding, but structural characterization of these changes has remained elusive. METHODOLOGY/PRINCIPAL FINDINGS: Here we use molecular dynamics simulations and exp...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408972/ https://www.ncbi.nlm.nih.gov/pubmed/18545669 http://dx.doi.org/10.1371/journal.pone.0002403 |