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Model for the Peptide-Free Conformation of Class II MHC Proteins

BACKGROUND: Major histocompatibility complex proteins are believed to undergo significant conformational changes concomitant with peptide binding, but structural characterization of these changes has remained elusive. METHODOLOGY/PRINCIPAL FINDINGS: Here we use molecular dynamics simulations and exp...

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Detalles Bibliográficos
Autores principales:	Painter, Corrie A., Cruz, Anthony, López, Gustavo E., Stern, Lawrence J., Zavala-Ruiz, Zarixia
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408972/ https://www.ncbi.nlm.nih.gov/pubmed/18545669 http://dx.doi.org/10.1371/journal.pone.0002403

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