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Olfactory Jump Reflex Habituation in Drosophila and Effects of Classical Conditioning Mutations
Habituation is a nonassociative learning mechanism, in which an initial response toward repeated stimuli gradually wanes. This is amongst the simplest and most widespread forms of behavioral plasticity. So far, neither the underlying molecular mechanisms nor the precise neural networks of habituatio...
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Formato: | Texto |
Lenguaje: | English |
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Informa Healthcare
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409173/ https://www.ncbi.nlm.nih.gov/pubmed/17464794 http://dx.doi.org/10.1080/01677060701247508 |
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author | Asztalos, Zoltan Arora, Neeraj Tully, Tim |
author_facet | Asztalos, Zoltan Arora, Neeraj Tully, Tim |
author_sort | Asztalos, Zoltan |
collection | PubMed |
description | Habituation is a nonassociative learning mechanism, in which an initial response toward repeated stimuli gradually wanes. This is amongst the simplest and most widespread forms of behavioral plasticity. So far, neither the underlying molecular mechanisms nor the precise neural networks of habituation are well understood. We have developed a novel paradigm to quantify habituation of the olfactory jump reflex in Drosophila. We present data demonstrating several behavioral properties of this phenomenon, generally observed in other species. We also show that the dunce and rutabaga memory mutants behave abnormally in this assay, suggesting that this assay might be used in behavioral screens for new mutants with defects in this simpler form of behavioral plasticity. |
format | Text |
id | pubmed-2409173 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | Informa Healthcare |
record_format | MEDLINE/PubMed |
spelling | pubmed-24091732008-06-12 Olfactory Jump Reflex Habituation in Drosophila and Effects of Classical Conditioning Mutations Asztalos, Zoltan Arora, Neeraj Tully, Tim J Neurogenet Article Habituation is a nonassociative learning mechanism, in which an initial response toward repeated stimuli gradually wanes. This is amongst the simplest and most widespread forms of behavioral plasticity. So far, neither the underlying molecular mechanisms nor the precise neural networks of habituation are well understood. We have developed a novel paradigm to quantify habituation of the olfactory jump reflex in Drosophila. We present data demonstrating several behavioral properties of this phenomenon, generally observed in other species. We also show that the dunce and rutabaga memory mutants behave abnormally in this assay, suggesting that this assay might be used in behavioral screens for new mutants with defects in this simpler form of behavioral plasticity. Informa Healthcare 2007 2007-10-15 /pmc/articles/PMC2409173/ /pubmed/17464794 http://dx.doi.org/10.1080/01677060701247508 Text en © 2007 Informa Healthcare http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Article Asztalos, Zoltan Arora, Neeraj Tully, Tim Olfactory Jump Reflex Habituation in Drosophila and Effects of Classical Conditioning Mutations |
title | Olfactory Jump Reflex Habituation in Drosophila and Effects of Classical Conditioning Mutations |
title_full | Olfactory Jump Reflex Habituation in Drosophila and Effects of Classical Conditioning Mutations |
title_fullStr | Olfactory Jump Reflex Habituation in Drosophila and Effects of Classical Conditioning Mutations |
title_full_unstemmed | Olfactory Jump Reflex Habituation in Drosophila and Effects of Classical Conditioning Mutations |
title_short | Olfactory Jump Reflex Habituation in Drosophila and Effects of Classical Conditioning Mutations |
title_sort | olfactory jump reflex habituation in drosophila and effects of classical conditioning mutations |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409173/ https://www.ncbi.nlm.nih.gov/pubmed/17464794 http://dx.doi.org/10.1080/01677060701247508 |
work_keys_str_mv | AT asztaloszoltan olfactoryjumpreflexhabituationindrosophilaandeffectsofclassicalconditioningmutations AT aroraneeraj olfactoryjumpreflexhabituationindrosophilaandeffectsofclassicalconditioningmutations AT tullytim olfactoryjumpreflexhabituationindrosophilaandeffectsofclassicalconditioningmutations |