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Olfactory Jump Reflex Habituation in Drosophila and Effects of Classical Conditioning Mutations

Habituation is a nonassociative learning mechanism, in which an initial response toward repeated stimuli gradually wanes. This is amongst the simplest and most widespread forms of behavioral plasticity. So far, neither the underlying molecular mechanisms nor the precise neural networks of habituatio...

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Autores principales: Asztalos, Zoltan, Arora, Neeraj, Tully, Tim
Formato: Texto
Lenguaje:English
Publicado: Informa Healthcare 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409173/
https://www.ncbi.nlm.nih.gov/pubmed/17464794
http://dx.doi.org/10.1080/01677060701247508
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author Asztalos, Zoltan
Arora, Neeraj
Tully, Tim
author_facet Asztalos, Zoltan
Arora, Neeraj
Tully, Tim
author_sort Asztalos, Zoltan
collection PubMed
description Habituation is a nonassociative learning mechanism, in which an initial response toward repeated stimuli gradually wanes. This is amongst the simplest and most widespread forms of behavioral plasticity. So far, neither the underlying molecular mechanisms nor the precise neural networks of habituation are well understood. We have developed a novel paradigm to quantify habituation of the olfactory jump reflex in Drosophila. We present data demonstrating several behavioral properties of this phenomenon, generally observed in other species. We also show that the dunce and rutabaga memory mutants behave abnormally in this assay, suggesting that this assay might be used in behavioral screens for new mutants with defects in this simpler form of behavioral plasticity.
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spelling pubmed-24091732008-06-12 Olfactory Jump Reflex Habituation in Drosophila and Effects of Classical Conditioning Mutations Asztalos, Zoltan Arora, Neeraj Tully, Tim J Neurogenet Article Habituation is a nonassociative learning mechanism, in which an initial response toward repeated stimuli gradually wanes. This is amongst the simplest and most widespread forms of behavioral plasticity. So far, neither the underlying molecular mechanisms nor the precise neural networks of habituation are well understood. We have developed a novel paradigm to quantify habituation of the olfactory jump reflex in Drosophila. We present data demonstrating several behavioral properties of this phenomenon, generally observed in other species. We also show that the dunce and rutabaga memory mutants behave abnormally in this assay, suggesting that this assay might be used in behavioral screens for new mutants with defects in this simpler form of behavioral plasticity. Informa Healthcare 2007 2007-10-15 /pmc/articles/PMC2409173/ /pubmed/17464794 http://dx.doi.org/10.1080/01677060701247508 Text en © 2007 Informa Healthcare http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Asztalos, Zoltan
Arora, Neeraj
Tully, Tim
Olfactory Jump Reflex Habituation in Drosophila and Effects of Classical Conditioning Mutations
title Olfactory Jump Reflex Habituation in Drosophila and Effects of Classical Conditioning Mutations
title_full Olfactory Jump Reflex Habituation in Drosophila and Effects of Classical Conditioning Mutations
title_fullStr Olfactory Jump Reflex Habituation in Drosophila and Effects of Classical Conditioning Mutations
title_full_unstemmed Olfactory Jump Reflex Habituation in Drosophila and Effects of Classical Conditioning Mutations
title_short Olfactory Jump Reflex Habituation in Drosophila and Effects of Classical Conditioning Mutations
title_sort olfactory jump reflex habituation in drosophila and effects of classical conditioning mutations
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409173/
https://www.ncbi.nlm.nih.gov/pubmed/17464794
http://dx.doi.org/10.1080/01677060701247508
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