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The Effect of Ethanol on the Release of Opioids from Oral Prolonged-Release Preparations
Recent experience has prompted the US FDA to consider whether ethanol ingestion may modify the release characteristics of prolonged-release formulations, where dose dumping may be an issue for patient safety. The influence of ethanol on the in vitro release of opioid drugs from some prolonged-releas...
Autores principales: | Walden, Malcolm, Nicholls, Fiona A., Smith, Kevin J., Tucker, Geoffrey T. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Informa Healthcare
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409176/ https://www.ncbi.nlm.nih.gov/pubmed/17882730 http://dx.doi.org/10.1080/03639040701377292 |
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