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Analysis of Polypeptide Movement in the SecY Channel during SecA-mediated Protein Translocation
In bacteria most secretory proteins are transported across the plasma membrane by the interplay of the ATPase SecA with the translocation channel formed by the SecY complex; SecA uses cycles of ATP hydrolysis to “push” consecutive segments of a polypeptide substrate through the channel. Here we have...
Autores principales: | Erlandson, Karl J., Or, Eran, Osborne, Andrew R., Rapoport, Tom A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409214/ https://www.ncbi.nlm.nih.gov/pubmed/18359943 http://dx.doi.org/10.1074/jbc.M710356200 |
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