The methionine synthase polymorphism D919G alters susceptibility to primary central nervous system lymphoma

Primary central nervous system lymphomas (PCNSL) frequently reveal genomic instability. We analysed different functional genetic variants affecting the folate and homocysteine metabolism important for DNA integrity in 31 PCNSL patients and 142 controls. We found significantly less carriers of the me...

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Detalles Bibliográficos
Autores principales: Linnebank, M, Schmidt, S, Kolsch, H, Linnebank, A, Heun, R, Schmidt-Wolf, I G H, Glasmacher, A, Fliessbach, K, Klockgether, T, Schlegel, U, Pels, H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409477/
https://www.ncbi.nlm.nih.gov/pubmed/15138479
http://dx.doi.org/10.1038/sj.bjc.6601777

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