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Late resistance to imatinib therapy in a metastatic gastrointestinal stromal tumour is associated with a second KIT mutation
Currently, there are no data on the secondary resistance of gastrointestinal stromal tumours to imatinib. Here, we report a case of metastatic gastrointestinal stromal tumour that relapsed during imatinib therapy. Mutation analysis showed that the imatinib-resistant liver tumour contained two c-kit...
Autores principales: | Wakai, T, Kanda, T, Hirota, S, Ohashi, A, Shirai, Y, Hatakeyama, K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409485/ https://www.ncbi.nlm.nih.gov/pubmed/15150562 http://dx.doi.org/10.1038/sj.bjc.6601819 |
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