Alteration of the copy number and deletion of mitochondrial DNA in human hepatocellular carcinoma

Somatic mutations in mitochondrial DNA (mtDNA) have been detected in hepatocellular carcinoma (HCC). However, it remains unclear whether mtDNA copy number and mitochondrial biogenesis are altered in HCC. In this study, we found that mtDNA copy number and the content of mitochondrial respiratory prot...

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Detalles Bibliográficos
Autores principales: Yin, P H, Lee, H C, Chau, G Y, Wu, Y T, Li, S H, Lui, W Y, Wei, Y H, Liu, T Y, Chi, C W
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409531/
https://www.ncbi.nlm.nih.gov/pubmed/15150555
http://dx.doi.org/10.1038/sj.bjc.6601838

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