SLIT2 promoter methylation analysis in neuroblastoma, Wilms' tumour and renal cell carcinoma

The 3p21.3 RASSF1A tumour suppressor gene (TSG) provides a paradigm for TSGs inactivated by promoter methylation rather than somatic mutations. Recently, we identified frequent promoter methylation without somatic mutations of SLIT2 in lung and breast cancers, suggesting similarities between SLIT2 a...

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Detalles Bibliográficos
Autores principales: Astuti, D, da Silva, N F, Dallol, A, Gentle, D, Martinsson, T, Kogner, P, Grundy, R, Kishida, T, Yao, M, Latif, F, Maher, E R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409544/
https://www.ncbi.nlm.nih.gov/pubmed/14735202
http://dx.doi.org/10.1038/sj.bjc.6601447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409544/
https://www.ncbi.nlm.nih.gov/pubmed/14735202
http://dx.doi.org/10.1038/sj.bjc.6601447

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