Germline mutations of the INK4a-ARF gene in patients with suspected genetic predisposition to melanoma

Germline anomalies of the INK4a-ARF and Cdk4 genes were sought in a series of 89 patients suspected of having a genetic predisposition to melanoma. Patients were selected based on the following criteria: (a) familial melanoma (23 cases), (b) multiple primary melanoma (MPM; 18 cases), (c) melanoma an...

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Detalles Bibliográficos
Autores principales: Soufir, N, Lacapere, J J, Bertrand, G, Matichard, E, Meziani, R, Mirebeau, D, Descamps, V, Gérard, B, Archimbaud, A, Ollivaud, L, Bouscarat, F, Baccard, M, Lanternier, G, Saïag, P, Lebbé, C, Basset-Seguin, N, Crickx, B, Cave, H, Grandchamp, B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409576/
https://www.ncbi.nlm.nih.gov/pubmed/14735200
http://dx.doi.org/10.1038/sj.bjc.6601503

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