Cargando…

Pharmacokinetics in mice and growth-inhibitory properties of the putative cancer chemopreventive agent resveratrol and the synthetic analogue trans 3,4,5,4′-tetramethoxystilbene

Resveratrol (trans-3,5,4′-trihydroxystilbene) is a naturally occurring polyphenol with cancer chemopreventive properties in preclinical models of carcinogenesis, including those of colorectal cancer. Recently, a variety of analogues of resveratrol have been synthesised and investigated in in vitro a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sale, S, Verschoyle, R D, Boocock, D, Jones, D J L, Wilsher, N, Ruparelia, K C, Potter, G A, Farmer, P B, Steward, W P, Gescher, A J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2004
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409587/ https://www.ncbi.nlm.nih.gov/pubmed/14760392 http://dx.doi.org/10.1038/sj.bjc.6601568

Ejemplares similares

Trans-3,4,5,4′-tetramethoxystilbene, a resveratrol analog, potently inhibits angiogenesis in vitro and in vivo
por: Chen, Liang-ke, et al.
Publicado: (2013)

Characterisation of metabolites of the putative cancer chemopreventive agent quercetin and their effect on cyclo-oxygenase activity
por: Jones, D J L, et al.
Publicado: (2004)

3′-hydroxy-3,4,5,4′-tetramethoxystilbene, the metabolite of resveratrol analogue DMU-212, inhibits ovarian cancer cell growth in vitro and in a mice xenograft model
por: Piotrowska-Kempisty, Hanna, et al.
Publicado: (2016)

Evaluation of the cancer chemopreventive efficacy of rice bran in genetic mouse models of breast, prostate and intestinal carcinogenesis
por: Verschoyle, R D, et al.
Publicado: (2007)

(Z)3,4,5,4′-trans-tetramethoxystilbene, a new analogue of resveratrol, inhibits gefitinb-resistant non-small cell lung cancer via selectively elevating intracellular calcium level
por: Fan, Xing-Xing, et al.
Publicado: (2015)

Enhanced biological activity of liposomal methylated resveratrol analog 3′-hydroxy-3,4,5,4′-tetramethoxystilbene (DMU-214) in 3D patient-derived ovarian cancer model
por: Nowicki, Andrzej, et al.
Publicado: (2022)

Steroidogenic activity of liposomal methylated resveratrol analog 3,4,5,4′-tetramethoxystilbene (DMU-212) in human luteinized granulosa cells in a primary three-dimensional in vitro model
por: Józkowiak, Małgorzata, et al.
Publicado: (2023)

Age-related difference in susceptibility of Apc(Min/+) mice towards the chemopreventive efficacy of dietary aspirin and curcumin
por: Perkins, S, et al.
Publicado: (2003)

Growth-inhibitory and cell cycle-arresting properties of the rice bran constituent tricin in human-derived breast cancer cells in vitro and in nude mice in vivo
por: Cai, H, et al.
Publicado: (2004)

The Effect of 3′-Hydroxy-3,4,5,4′-Tetramethoxy -stilbene, the Metabolite of the Resveratrol Analogue DMU-212, on the Motility and Proliferation of Ovarian Cancer Cells
por: Nowicki, Andrzej, et al.
Publicado: (2020)

3,4,5,4′-trans-tetramethoxystilbene (DMU-212) modulates the activation of NF-κB, AP-1, and STAT3 transcription factors in rat liver carcinogenesis induced by initiation-promotion regimen
por: Cichocki, Michał, et al.
Publicado: (2014)

The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYP1B1
por: Potter, G A, et al.
Publicado: (2002)

Analysis of resveratrol as a lung cancer chemopreventive agent in A/J mice exposed to benzo[a]pyrene
por: Berge, G, et al.
Publicado: (2004)

trans-3,3′,4,5′-Tetramethoxystilbene
por: Yan, Ri-An, et al.
Publicado: (2011)

A methoxy derivative of resveratrol analogue selectively induced activation of the mitochondrial apoptotic pathway in transformed fibroblasts
por: Gosslau, A, et al.
Publicado: (2005)

Antimicrobial Octapeptin C4 Analogues Active against Cryptococcus Species
por: Chitty, Jessica L., et al.
Publicado: (2018)

Identification of human-selective analogues of the vascular-disrupting agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)
por: Tijono, S M, et al.
Publicado: (2013)

Cancer chemoprevention: lessons learned and future directions
por: Brenner, D E, et al.
Publicado: (2005)

Nonantioxidant Tetramethoxystilbene Abrogates α-Synuclein-Induced Yeast Cell Death but Not That Triggered by the Bax or βA4 Peptide
por: Derf, Asma, et al.
Publicado: (2018)

Monthly malaria chemoprevention shows potential in an area of very high, perennial malaria transmission
por: Cairns, Matthew, et al.
Publicado: (2015)

Determinants of operative time in thyroid surgery: A prospective multicenter study of 3454 thyroidectomies
por: Patoir, Arnaud, et al.
Publicado: (2017)

Evaluation of the incremental cost to the National Health Service of prescribing analogue insulin
por: Holden, Sarah E, et al.
Publicado: (2011)

Resveratrol analogue 4,4′-dihydroxy-trans-stilbene potently inhibits cancer invasion and metastasis
por: Savio, Monica, et al.
Publicado: (2016)

Novel thalidomide analogues display anti-angiogenic activity independently of immunomodulatory effects
por: Dredge, K, et al.
Publicado: (2002)

TRAIL-expressing mesenchymal stem cells kill the putative cancer stem cell population
por: Loebinger, M R, et al.
Publicado: (2010)

Resveratrol increases BRCA1 and BRCA2 mRNA expression in breast tumour cell lines
por: Fustier, P, et al.
Publicado: (2003)

Antitumour 2-(4-aminophenyl)benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo
por: Leong, C-O, et al.
Publicado: (2003)

TBAJ-876, a 3,5-Dialkoxypyridine Analogue of Bedaquiline, Is Active against Mycobacterium abscessus
por: Sarathy, Jickky Palmae, et al.
Publicado: (2020)

A novel inhibitor of the PI3K/Akt pathway based on the structure of inositol 1,3,4,5,6-pentakisphosphate
por: Falasca, M, et al.
Publicado: (2010)

Expression of V(1A) and GRP receptors leads to cellular transformation and increased sensitivity to substance-P analogue-induced growth inhibition
por: MacKinnon, A C, et al.
Publicado: (2005)

Vitamin E analogues as inducers of apoptosis: structure–function relation
por: Birringer, M, et al.
Publicado: (2003)

Multifactorial anticancer effects of digalloyl-resveratrol encompass apoptosis, cell-cycle arrest, and inhibition of lymphendothelial gap formation in vitro
por: Madlener, S, et al.
Publicado: (2010)

Potentiation of the anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the kinase inhibitor Staurosporine or its clinically relevant analogue UCN-01
por: Yeow, W-S, et al.
Publicado: (2006)

Role of Annexin A5 on Mitochondria-Dependent Apoptosis Induced by Tetramethoxystilbene in Human Breast Cancer Cells
por: Hong, Mihye, et al.
Publicado: (2014)

Rescue of primary ubiquinone deficiency due to a novel COQ7 defect using 2,4–dihydroxybensoic acid
por: Freyer, Christoph, et al.
Publicado: (2015)

Antimicrobial Activity of Resveratrol Analogues
por: Chalal, Malik, et al.
Publicado: (2014)

Chemoprevention of Experimental Periodontitis in Diabetic Rats with Silk Fibroin Nanoparticles Loaded with Resveratrol
por: Giménez-Siurana, Ana, et al.
Publicado: (2020)

Oestrogen inhibits resveratrol-induced post-translational modification of p53 and apoptosis in breast cancer cells
por: Zhang, S, et al.
Publicado: (2004)

‘1-8 interferon inducible gene family’: putative colon carcinoma-associated antigens
por: Tirosh, B, et al.
Publicado: (2007)

1α,25-Dihydroxyvitamin D(3) (calcitriol) and its analogue, 19-nor-1α,25(OH)(2)D(2), potentiate the effects of ionising radiation on human prostate cancer cells
por: Dunlap, N, et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_r3gl4th50ppetrle95t9f66vf1