TNF autovaccination induces self anti-TNF antibodies and inhibits metastasis in a murine melanoma model

TNF is a proinflammatory cytokine involved in the pathogenesis of chronic inflammatory diseases, but also in metastasis in certain types of cancer. In terms of therapy, TNF is targeted by anti-TNF neutralising monoclonal antibodies or soluble TNF receptors. Recently, a novel strategy based on the ge...

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Detalles Bibliográficos
Autores principales: Waterston, A M, Salway, F, Andreakos, E, Butler, D M, Feldmann, M, Coombes, R C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409655/
https://www.ncbi.nlm.nih.gov/pubmed/15026813
http://dx.doi.org/10.1038/sj.bjc.6601670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409655/
https://www.ncbi.nlm.nih.gov/pubmed/15026813
http://dx.doi.org/10.1038/sj.bjc.6601670

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