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TNF autovaccination induces self anti-TNF antibodies and inhibits metastasis in a murine melanoma model
TNF is a proinflammatory cytokine involved in the pathogenesis of chronic inflammatory diseases, but also in metastasis in certain types of cancer. In terms of therapy, TNF is targeted by anti-TNF neutralising monoclonal antibodies or soluble TNF receptors. Recently, a novel strategy based on the ge...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409655/ https://www.ncbi.nlm.nih.gov/pubmed/15026813 http://dx.doi.org/10.1038/sj.bjc.6601670 |