Loss of heterozygosity on 10q and mutational status of PTEN and BMPR1A in colorectal primary tumours and metastases

We investigated the possible role of chromosome 10q losses in colorectal cancer metastasis by carrying out an allelic imbalance study on a series of microsatellite instability-negative (MSI−) primary tumours (n=32) and metastases (n=36) from 49 patients. Our results demonstrate that 10q allelic loss...

Descripción completa

Detalles Bibliográficos
Autores principales: Karoui, M, Tresallet, C, Julie, C, Zimmermann, U, Staroz, F, Brams, A, Muti, C, Boulard, C, Robreau, A-M, Puy, H, Malafosse, R, Penna, C, Pruvot, F-R, Thiery, J P, Boileau, C, Rougier, P, Nordlinger, B, Radvanyi, F, Franc, B, Hofmann-Radvanyi, H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409663/
https://www.ncbi.nlm.nih.gov/pubmed/15026806
http://dx.doi.org/10.1038/sj.bjc.6601687

Ejemplares similares

Ejemplares similares