Transduction of dendritic cells with recombinant adenovirus encoding HCA661 activates autologous cytotoxic T lymphocytes to target hepatoma cells

Transduction of recombinant adenovirus into dendritic cells (DCs) is a promising new tool for cancer vaccine development. Here, we report that an adenovirus vector carrying hepatocellular carcinoma (HCC) antigen HCA661 and infected into DCs generates T-cell immunity against hepatoma cells. HCA661 is...

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Detalles Bibliográficos
Autores principales: Chan, R C-F, Pang, X-W, Wang, Y-D, Chen, W-F, Xie, Y
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409703/
https://www.ncbi.nlm.nih.gov/pubmed/15083197
http://dx.doi.org/10.1038/sj.bjc.6601706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409703/
https://www.ncbi.nlm.nih.gov/pubmed/15083197
http://dx.doi.org/10.1038/sj.bjc.6601706

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