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Transduction of dendritic cells with recombinant adenovirus encoding HCA661 activates autologous cytotoxic T lymphocytes to target hepatoma cells

Transduction of recombinant adenovirus into dendritic cells (DCs) is a promising new tool for cancer vaccine development. Here, we report that an adenovirus vector carrying hepatocellular carcinoma (HCC) antigen HCA661 and infected into DCs generates T-cell immunity against hepatoma cells. HCA661 is...

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Detalles Bibliográficos
Autores principales:	Chan, R C-F, Pang, X-W, Wang, Y-D, Chen, W-F, Xie, Y
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2004
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409703/ https://www.ncbi.nlm.nih.gov/pubmed/15083197 http://dx.doi.org/10.1038/sj.bjc.6601706

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