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Porphyrin synthesis from ALA derivatives for photodynamic therapy. In vitro and in vivo studies

The aim of this work was to test in vitro and in vivo the efficacy of the derivatives of 5-aminolevulinic acid (ALA): hexyl-ALA (He-ALA), undecanoyl-ALA and R,S-2-(hydroximethyl)tetrahydropyranyl-ALA (THP-ALA) as pro-photosensitising agents. The compounds were assayed in a cell line derived from a m...

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Detalles Bibliográficos
Autores principales:	Perotti, C, Fukuda, H, DiVenosa, G, MacRobert, A J, Batlle, A, Casas, A
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2004
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409714/ https://www.ncbi.nlm.nih.gov/pubmed/15083200 http://dx.doi.org/10.1038/sj.bjc.6601722

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