Interaction between cyclooxygenase-2 gene polymorphism and dietary n-6 polyunsaturated fatty acids on colon cancer risk: The Singapore Chinese Health Study

This case–control study of 310 colorectal cancer cases and 1177 controls in a nested prospective, population-based cohort of Singapore Chinese subjects found a statistically significant association between the cyclooxygenase (COX)-2 −765G>C gene polymorphism and colon cancer risk among high consu...

Descripción completa

Detalles Bibliográficos
Autores principales: Koh, W-P, Yuan, J-M, van den Berg, D, Lee, H-P, Yu, M C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Epidemiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409730/
https://www.ncbi.nlm.nih.gov/pubmed/15150618
http://dx.doi.org/10.1038/sj.bjc.6601797
Descripción
Sumario:This case–control study of 310 colorectal cancer cases and 1177 controls in a nested prospective, population-based cohort of Singapore Chinese subjects found a statistically significant association between the cyclooxygenase (COX)-2 −765G>C gene polymorphism and colon cancer risk among high consumers of dietary n-6 polyunsaturated fatty acids (odds ratio=2.38, 95% confidence interval=1.23–4.59).

Ejemplares similares