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A novel biweekly multidrug regimen of gemcitabine, oxaliplatin, 5-fluorouracil (5-FU), and folinic acid (FA) in pretreated patients with advanced colorectal carcinoma
Previous results suggest that GEM affects 5-fluorouracil (5-FU) metabolism and pharmacokinetics in cancer patients, while combined with oxaliplatin, levo-folinic acid, and 5-FU (GOLF regimen), at doses achievable in cancer patients, determines high cytotoxic and proapoptotic antitumour activity in c...
Autores principales: | Correale, P, Messinese, S, Caraglia, M, Marsili, S, Piccolomini, A, Petrioli, R, Ceciarini, F, Micheli, L, Nencini, C, Neri, A, Vuolo, G, Guarnieri, A, Abbruzzese, A, Prete, S D, Giorgi, G, Francini, G |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409742/ https://www.ncbi.nlm.nih.gov/pubmed/15150625 http://dx.doi.org/10.1038/sj.bjc.6601783 |
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